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Monkeypox Response


Monkeypox Response

Monkeypox information and guidance

The current risk of getting monkeypox (MPX) in the general public is very low.

MPX is primarily spreading through prolonged skin-on-skin contact, including sexual contact. Right now, MPX is disproportionately impacting gay and bisexual men and transgender people in San Mateo County, but anyone can contract MPX. Activities that may increase a person’s risk for contracting MPX may include having sex or direct physical contact with multiple or new partners, attending crowded parties or clubs where sex is occurring on-premises, or having direct physical contact with someone who is feeling sick or has a rash. Taking steps to avoid prolonged skin-on-skin contact can reduce your risk of getting MPX.

Guidance on MPX, current case rates, and vaccine information is available below. San Mateo County residents who meet eligibility guidelines can schedule a vaccination appointment on the MyTurn website. If you meet the eligibility guidelines but are unable to schedule an appointment, sign up to be notified about upcoming MPX vaccination opportunities using the vaccination request form

If you have questions about MPX, send an email to


Monkeypox Vaccination Opportunities

The Centers for Disease Control and Prevention (CDC) and the California Department of Public Health (CDPH) recommend that people who have been exposed to monkeypox (MPX) be given the vaccine to prevent them from developing the disease – this is called post-exposure prophylaxis or PEP. 

PEP can also be given to people who do not have a known exposure but are at risk for recent exposure to MPX cases. SMC Health is offering twice weekly PEP clinics on Monday and Thursday, check MyTurn for available appointments up to 48-hours ahead of the clinic day.  


Vaccination Request Form

San Mateo County residents who meet eligibility guidelines for higher risk for monkeypox (MPX) may sign up to be notified about upcoming vaccination opportunities, including weekly clinics offered by County Health.


Information & Guidance

About Monkeypox

Monkeypox (MPX) is a rare disease that is caused by infection with the MPX virus. Most cases resolve on their own, though they can be serious. The illness often begins with flu-like symptoms before the emergence of a rash and may last for 2 to 4 weeks. While it’s good to stay alert about any emerging public health outbreaks, the current risk of getting MPX in the general public is very low.