Skip to main content Skip to site navigation

Mpox Vaccination Opportunities


In preparation for the summer season and Pride celebrations in the Bay Area, San Mateo County Health urges at-risk individuals to protect themselves against the mpox virus, which spreads through prolonged skin-to-skin contact and bodily fluids from sexual contact or close sustained physical contact.

County Health strongly encourages vaccination for those populations likely to be most impacted as mpox increases in the Bay Area. These populations include persons living with HIV, anyone taking or eligible to take HIV PrEP, and all men, trans people and non-binary people who have sex with men, trans people or non-binary people.

Additional information about mpox prevention is available from the Centers for Disease Control and Prevention.

Anyone who wants protection against mpox should seek the vaccine. For the best protection, they should receive two doses of the Jynneos orthopox vaccine at least 28 days apart.

Since peak immunity is reached 14 days after the second dose, people interested in getting vaccinated should get their first dose as soon as possible. If it has been at least 28 days since your first dose, you are eligible to receive your second dose at any time.

Since no vaccine is one hundred percent effective, it is important to reduce risk of potential exposures to mpox both before and after being vaccinated.

Local Resources for Mpox Vaccination

California Department of Public Health’s Online Vaccination Portal.

San Mateo County Health’s Edison STD Clinic (by appointment only)
222 West 39th Avenue, First Floor, San Mateo
Monday – Friday, 8:30 a.m. – 4:30 p.m.
(650) 573-2385

San Mateo County Pride Celebration (mpox vaccine walk-up clinic available)
Saturday June 10, 11 a.m. – 5 p.m.
San Mateo Central Park

Alameda County (Alameda County residents only)

Contra Costa County 

San Francisco 

Santa Clara County